Oxandrolone is an anabolic steroid created by Searle Laboratories under the trademark Anavar, and introduced into the US in 1964. It is taken orally, and unlike other steroids delivered in this manner, most of which are Class II steroids, the majority of its effects are due to reaction with the androgen receptor. In sufficient dosage, Oxandrolone is highly likely to bind well with the receptor, and is therefore a Class I steroid, while having few other side-effects.
Partly this is due to its apparent lack of non-AR-mediated activity. This can be corrected of course by stacking with a Class II steroid such as Anabol, Anapolon: the latter two steroids require high blood levels which are not obtained by oral use of the powders.
The other part of the reason for this is that bodybuilders make unfortunate and unreasonable comparisons when judging anabolic steroids. If say 8 tablets per day does little, then the drug is pronounced useless or weak by the user. But that is only 20 mg/day, or 140 mg/week. Does 140 mg/week testosterone give much results? No. Few anabolic steroids give dramatic results at that dose. Per milligram the potency is reasonable, but each individual tablet is weak because the dosage is small.
Anavar does not aromatize or convert to DHT, and has a longer half life than Anabol - 8 hours vs. 4 hours. Thus, a moderate dose taken in the morning is largely out of the system by night, yet supplies reasonable levels of androgen during the day and early evening.
Although Anavar is an oral steroid, and has been alpha-alkylated to survive oral ingestion and the first pass through the liver, it´s still relatively mild in that respect too..., the unique chemical configuration of oxandrolone both confers a resistance to liver metabolism as well as noticable anabolic activity. It would also appear that Anavar appears not to exhibit the serious hepatotoxic effects (jaundice, cholestatic hepatitis, peliosis hepatis, hyperplasias and neoplasms) typically attributed to the C17alpha-alkylated AASs. Anavar has even been used successfully in some studies to heal cutaneous wounds, or to improve respiratory function. Both of these novel properties could make it a good choice for in-season use for boxers, Mixed Martial Arts competitors, and other such athletes.
Now here´s some interesting stuff for anyone interested primarily in the fat loss properties of this stuff: Anavar may be what we´d call a "fat-burning steroid". Abdominal and visceral fat were both reduced in one study when subjects in the low/normal natural testosterone range used anavar. In another study, appendicular, total, and trunk fat were all reduced with a relatively small dose of 20mgs/day, and no exercise. In addition, weight gained with Anavar may be nearly permanent too. It might not be much, but you´ll stand a good chance of keeping most of it. In one study, subjects maintained their weight (re)gains from anavar for at least 6 months after cessation! Concomitantly, in another study, Twelve weeks after discontinuing oxandrolone, 83% of the reductions in total, trunk, and extremity fat were also sustained! If you´re regaining weight, Anavar will give you nearly permanent gains, and if you are trying to lose fat (and you keep your diet in check), the fat lost with Anavar is basically looks to be nearly permanent.
Anavar is great for strength and cutting purposes, but not for bulking or a lot of weight gain.
Effective dose: (Men)20-100mgs/day (or .125mg/kg~bdywt); (Women) 2.5-20mgs.day
Active Life: 8-12 hours
Detection Time: 3 weeks
Anabolic/Androgenic Ratio (Range): 322-630:24
Store in temperature not exceeding 77oF(25oC), away from excess moisture.