Ketotifen Fumarate(Astafen) is an H1-antihistamine that is available in two versions oral and ophthalmic. In the ophthalmic (for use in the eye) form, it is used to treat conjunctivitis (pink eye), or the itchy red eyes caused by allergies. It is used orally as a medication to aid in the prevention of asthma attacks, and has also been used by many as a sleeping aid and appetite stimulant.
Ketotifen inhibits down regulation of beta receptors, which are often degraded by fat-burners such as Clenbuterol.
It can be used in combination with these other drugs in order to keep feeling their fat-burning effects for longer periods of time with out the need for periods of on and off cycling. Side effects can include drowsiness, irritability, nosebleeds and dry mouth. Ketoifen increases appetite; therefore another side effect is typically weight gain. Ketotifen also (potentially) improves insulin sensitivity within muscle tissue.
Because Ketotifen has the ability to stimulate the appetite, it has been studied for use with wasting conditions. In the most commonly referenced study examining this property, 22 AIDS patients who were administered Ketotifen and Oxymetholone(Anapolon), 18 gained an average of 11.4 pounds after just under 4 weeks. Further research proved Ketotifen to be a TNF-alpha blocker. TNF-alpha lowers testosterone and IGF-1 levels immensely while strenuous exercise raises TNF-alpha levels. TNF-alpha has also been found to inhibit the muscle's ability to uptake glucose, (which is known as insulin resistance). It has recently been discovered that hypogonadism and low testosterone are also associated with elevated TNF-alpha.
This would seem to indicate a potential use for Ketotifen in Post-Cycle Therapy.
Store in temperature not exceeding 77oF(25oC), away from excess moisture.