Bromocriptine(Gynodel, Parlodel) is a dopamine agonist drug (meaning it acts like dopamine in the brain), primarily activating the dopamine D2 receptors. It's main use is for the treatment of high prolactin, Parkinson's disease, and acromegaly; it was also used by bodybuilders in the 80's for it's GH releasing properties. However, it's metabolic effects are far greater than that.
Amenorrhea, female infertility, galactorrhea, hypogonadism, and acromegaly may all be caused by pituitary problems, such as hyperprolactinaemia, and therefore, these problems may be treated by this drug.
Since bromocryptine acts as a dopamine agonist, it has potential use in treating cocaine addiction, since the addictive effects of cocaine are caused by it blocking dopamine reuptake. Although it has negligible subjective effects when administered alone, studies show it has the potential to significantly ease the cocaine withdrawal syndrome.
There appear to be some connections between insulin insensitivity and dopamine. A company called Veroscience is using bromocriptine to treat diabetes and obesity, and their website postulates a connection between neurotransmitters and seasonal variation in insulin sensitivity among vetebrate animals. There are also some connections between temperature and dopamine and serotonin production. In addition, new research indicates that patients with diabetes are more likely to develop parkinson's disease, which is characterized by a dopamine deficiency in the brain.
In genetically obese rats, bromocriptine normalizes metabolism and there are many good reasons to think it will do the same in humans. Bromocriptine has use during dieting (to minimize the negative adaptations), muscle gain when very lean, and may be beneficial post-steroid cycle. It may also be useful for diabetes treatment and may have pro-sexual effects.
Though commonly prescribed for the treatment of pituitary tumors resulting in heavy prolactin secretion the drug has found itself in a newer position as a sexual stimulant. This is simply explained since the drug is a dopamine agonist with profound stimulatory effects upon the brains D-2 receptors. The sexual side of this drugs effects coupled with the antiprolactin value. The result is leaner more muscular individuals that are obviously hornier as well.
Bromocriptine has a half-life of roughly 12-14 hours, and dosing is 2.5-5 mg/day taken in the morning.
Store in temperature not exceeding 77oF(25oC), away from excess moisture.